<div id="ldPlotDesc" title="Linkage Disequilibrium Plots">
    <p>
        The following are linkage disequilibrium (LD) plots, which we have constructed
        per gene.
    </p>
    <p>
        Non-random associations between polymorphisms at different loci are measured by
        the degree of linkage disequilibrium. Linkage disequilibrium is generally caused
        by genetic linkage and the rate of recombination; mutation rate; random drift or
        non-random mating; and population structure.
    </p>
    <p>
        An LD plot enables one to quickly determine the extent of disequilibrium between
        genetic marker pairs. Our LD plots were contructed by the
        <a href="http://www.broad.mit.edu/mpg/haploview/" target="new">Haploview</a>
        program using the correlation coefficient r<sup>2</sup> as the measure of linkage disequilibrium.
        A value of r<sup>2</sup>=0 (indicating no correlation) is represented by a white cell, whereas a
        value of r<sup>2</sup>=1 (indicating perfect correlation) is represented by a black cell. Intermediate
        color intensities signify correlations between zero and one.
    </p>
</div>